Bovine ALB ELISA Kit

The outbreak of the 2019-nCoV infection began in December 2019 in Wuhan, Hubei province, and rapidly spread to many provinces in China as well as other countries. Here we report the epidemiological, clinical, laboratory, and radiological characteristics, as well as potential biomarkers for predicting disease severity in 2019-nCoV-infected patients in Shenzhen, China. All 12 cases of the 2019-nCoV-infected patients developed pneumonia and half of them developed acute respiratory distress syndrome (ARDS). The most common laboratory abnormalities were hypoalbuminemia, lymphopenia, decreased percentage of lymphocytes (LYM) and neutrophils (NEU), elevated C-reactive protein (CRP) and lactate dehydrogenase (LDH), and decreased CD8 count. The viral load of 2019-nCoV detected from patient respiratory tracts was positively linked to lung disease severity. ALB, LYM, LYM (%), LDH, NEU (%), and CRP were highly correlated to the acute lung injury. Age, viral load, lung injury score, and blood biochemistry indexes, albumin (ALB), CRP, LDH, LYM (%), LYM, and NEU (%), may be predictors of disease severity. Moreover, the Angiotensin II level in the plasma sample from 2019-nCoV infected patients was markedly elevated and linearly associated to viral load and lung injury. Our results suggest a number of potential diagnosis biomarkers and angiotensin receptor blocker (ARB) drugs for potential repurposing treatment of 2019-nCoV infection.

Current filtering methods of airborne LIDAR bathymetry (ALB) point clouds cannot identify negative anomalies or avoid over-filtering of the data. To overcome these problems, we propose a bidirectional cloth simulation filtering (BCSF) method and verify it using captured data. First, a transfer iterative trend surface is established to eliminate the negative anomalies and realize the continuous expression of the seafloor topography. The terrain complexities of the seafloor points are calculated using four extracted feature factors: slope, standard deviation of depth, Gaussian curvature, and roughness. We then calculate the sub-regional terrain complexity and the adaptive distance threshold and obtain user-defined parameters. Finally, sub-regional filtering is carried out, and a filtered surface is established to solve the over-filtering problem of convex and concave seafloor topographies based on the BCSF correction model. To evaluate the performance of the proposed method, the BCSF method was applied to ALB data captured around Yuanzhi Island in the South China Sea. The experimental results show that the BCSF method effectively filters out non-seafloor points and fully preserves the seafloor microtopography to realize the integrity of the seafloor topography. The proposed BCSF method outperforms the cloth simulation filtering method in terms of the elimination rate, which decreases from 38.78% to 2.52% and from 29.52% to 0.70% in the whole study area and local study area, respectively. Consequently, the BCSF method that combines forward filtering with inverse filtering exhibits complementary advantages, avoids over-filtering, and demonstrates strong adaptability and robustness for ALB data.