BGN blocking peptide (DAG-P1412)

Synthetic BGN blocking peptide for BL Datasheet

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Found in several connective tissues, especially in articular cartilages.
Sequence Similarities
Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.Contains 12 LRR (leucine-rich) repeats.
Cellular Localization
Secreted > extracellular space > extracellular matrix.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
UniProt ID
Antigen Description
The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to two other small proteoglycans, decorin and fibromodulin. The encoded protein and decorin are thought to be the result of a gene duplication. Decorin contains one attached glycosaminoglycan chain, while this protein probably contains two chains. For this reason, this protein is called biglycan. This protein plays a role in assembly of collagen fibrils and muscle regeneration. It interacts with several proteins involved in muscular dystrophy, including alpha-dystroglycan, alpha- and gamma-sarcoglycan and collagen VI, and it is critical for the assembly of the dystrophin-associated protein complex. [provided by RefSeq, Nov 2009]
extracellular matrix binding; extracellular matrix structural constituent; glycosaminoglycan binding;
BGN; biglycan; PGI; DSPG1; PG-S1; SLRR1A; biglycan proteoglycan; bone/cartilage proteoglycan I; bone/cartilage proteoglycan-I; small leucine-rich protein 1A; dermatan sulphate proteoglycan I;


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