Human VTCN1 blocking peptide

Name: Human VTCN1 blocking peptide
SKU: CDBP0548
Rating: 5 (1 reviews)

Synthetic Human VTCN1 blocking peptide for Apuri, BL, ELISA

COA

SDS

Datasheet

Summary

Product Overview

Blocking/Immunizing peptide for anti-B7-H4 antibody

Target

B7-H4

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

79679

Antigen Description

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]

Function

receptor binding;

Synonyms

VTCN1; V-set domain containing T cell activation inhibitor 1; B7X; B7H4; B7S1; B7-H4; B7h.5; VCTN1; PRO1291; V-set domain-containing T-cell activation inhibitor 1; B7 family member, H4; B7 superfamily member 1; T cell costimulatory molecule B7x; T-cell costimulatory molecule B7x; immune costimulatory protein B7-H4;

Citations

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Documents

pdf COA

pdf SDS

pdf Datasheet

QA & Reviews

Customer Reviews

References

Nardilysin-dependent proteolysis of cell-associated VTCN1: A novel pathway and biomarker of type 1 diabetes development

JOURNAL OF IMMUNOLOGY

Authors: Savinov, Alexei; Radichev, Ilian; Maneva-Radicheva, Lilia; Amatya, Christina; Parker, Camille; Ellefson, Jacob; Wasserfall, Clive; Atkinson, Mark; Burn, Paul

Abstract

The inhibitory T cell co-receptor molecule B7-H4 (VTCN1) regulates major histocompatibility complex class I expression in a stem cell-derived model of primitive human trophoblast development

HUMAN REPRODUCTION

Authors: Zhou, J.; Karvas, R.; Schulz, L.; Ezashi, T.; Roberts, R. M.; Schust, D.

Abstract