Tag/Conjugate
Unconjugated
Molecular Weight
200-220 kDa
Alternative Names
Filamentous hemagglutinin; Bordetella pertussis FHA; B. pertussis FHA
Buffer
lyophilized from 0.05 M Tris HCL, pH 8, with 0.5 M sodium chloride and 5% sucrose
Warnings
PLEASE note that this product is intended for research use only; not for diagnostic or clinical use.
Introduction
The filamentous haemagglutinin adhesin (FHA) is a large, filamentous protein that serves as a dominant attachment factor for adherence to host ciliated epithelial cells of the respiratory tract, called respiratory epithelium. It is associated with biofilm formation and possesses at least four binding domains which can bind to different cell receptors on the epithelial cell surface. One notable bacterium that produces filamentous haemagglutinin adhesin is Bordetella pertussis, which uses this protein as a virulence factor.
Keywords
Bordetella pertussis FHA; B. pertussis FHA; Bordetella pertussis Filamentous hemagglutinin; FHA; Filamentous hemagglutinin; Filamentous hemagglutinin antigen; Pertussis FHA; FHA protein; Anti-HA FHA Hemagglutinin