Filamentous hemagglutinin; Bordetella pertussis FHA; B. pertussis FHA
Format
Lyophilized Powder
Buffer
lyophilized from 0.05 M Tris HCL, pH 8, with 0.5 M sodium chloride and 5% sucrose
Preservative
None
Storage
Store at 2-8°C
Introduction
The filamentous haemagglutinin adhesin (FHA) is a large, filamentous protein that serves as a dominant attachment factor for adherence to host ciliated epithelial cells of the respiratory tract, called respiratory epithelium. It is associated with biofilm formation and possesses at least four binding domains which can bind to different cell receptors on the epithelial cell surface. One notable bacterium that produces filamentous haemagglutinin adhesin is Bordetella pertussis, which uses this protein as a virulence factor.
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