Anti-Macrophage surface antigen monoclonal antibody (DMAB14253)
Mouse anti-Human Macrophage surface antigen monoclonal antibody for IHC
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Native human alveolar macrophages.
Immunohistochemistry (10 μg/mL) & The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
AM-3K; Mouse Anti-macrophage surface antigen Monoclonal Antibody; Anti-macrophage surface antigen Monoclonal Antibody; macrophage surface antigen Monoclonal Antibody Mouse Anti-macrophage surface antigen MAb; Anti-macrophage surface antigen MAb; macrophag
AM-3K, was produced by using human alveolar macrophages as immunogen. BN-4Lreacts intensely with most of macrophages in lymphoreticular organs and in many other organs and tissues. BN-4Lalso reacts with the macrophages in many pathological conditions. However, this antibody does not react with dendritic cell population, such as epidermal Langerhans cells, interdigitating cells in the paracortex of lymph nodes, nor follicular dendritic cells. Lymphocytes, granulocytes and freshly isolated blood monocytes are also negative. Reaction products forBN-4Lwere found on the cytoplasmic membrane of macrophages by immunoelectron microscopy.
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Lin, YF; Lee, HM; et al. The essentiality of PKC alpha and PKC beta(1) translocation for CD14(+) monocyte differentiation towards macrophages and dendritic cells, respectively. JOURNAL OF CELLULAR BIOCHEMISTRY 102:429-441(2007).
Forbes, SJ; Eschmann, M; et al. Inhibition of Salmonella enterica serovar Typhimurium motility and entry into epithelial cells by a protective antilipopolysaccharide monoclonal immunoglobulin a antibody. INFECTION AND IMMUNITY 76:4137-4144(2008).
Custom Antibody Labeling
We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody.