Anti-Macrophage surface antigen monoclonal antibody (DMAB14253)

Mouse anti-Human Macrophage surface antigen monoclonal antibody for IHC Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
BN-4L
Species Reactivity
Human
Immunogen
Native human alveolar macrophages.
Conjugate
Unconjugated

Applications


Application Notes
Immunohistochemistry (10 μg/mL) & The optimal working dilution should be determined by the end user.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
AM-3K; Mouse Anti-macrophage surface antigen Monoclonal Antibody; Anti-macrophage surface antigen Monoclonal Antibody; macrophage surface antigen Monoclonal Antibody Mouse Anti-macrophage surface antigen MAb; Anti-macrophage surface antigen MAb; macrophag

Product Background


Antigen Description
AM-3K, was produced by using human alveolar macrophages as immunogen. BN-4Lreacts intensely with most of macrophages in lymphoreticular organs and in many other organs and tissues. BN-4Lalso reacts with the macrophages in many pathological conditions. However, this antibody does not react with dendritic cell population, such as epidermal Langerhans cells, interdigitating cells in the paracortex of lymph nodes, nor follicular dendritic cells. Lymphocytes, granulocytes and freshly isolated blood monocytes are also negative. Reaction products forBN-4Lwere found on the cytoplasmic membrane of macrophages by immunoelectron microscopy.

Citations


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References


Mitra, S; Foster, TH; et al. In vivo optical imaging to visualize photodynamic therapy-induced immune responses. BIOPHOTONICS AND IMMUNE RESPONSES IV 7178:-(2009).
Hui, G; Hashimoto, C; et al. The requirement of CD80, CD86, and ICAM-1 on the ability of adjuvant formulations to potentiate antibody responses to a Plasmodium falciparum blood-stage vaccine. VACCINE 25:8549-8556(2007).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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