Mouse Anti Human GD2 glycolipid Hybridoma [WJO-JT-67] (CSC-H2944)

This hybridoma produces mAbs (IgM) against Human GD2 glycolipid

General Information


Immunogen
Human GD2 glycolipid
Isotype
IgM
Fusion Species
Mouse X Mouse Hybridoma
Immunological Donor
BALB/c Mouse
Myeloma
Mouse SP2/0
Clone
WJO-JT-67
Cell Line Description
The hybridoma produces monoclonal antibody against Human GD2 glycolipid

Culture Method


Storage
Liquid nitrogen vapor phase.

Target


Introduction
GD2 is a disialoganglioside expressed on tumors of neuroectodermal origin, including human neuroblastoma and melanoma, with highly restricted expression on normal tissues, principally to the cerebellum and peripheral nerves in humans.
The relatively tumor specific expression of GD2 makes it a suitable target for immunotherapy with monoclonal antibodies or with artificial T cell receptors.

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