Rabbit Anti-Human ZFP64 (a.a. 357-681) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human ZFP64 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 357-681 aa of BC041622

Conjugate

Application Notes

WB: 1:500-1:1000

General Notes

This product (Catalog No. DPABH-01707) is a rabbit-derived polyclonal antibody raised against human ZFP64, targeting the amino acid region 357–681 of the protein. This antibody exhibits cross-reactivity with Human ZFP64 from mouse and rat. It has been affinity purified by Protein A. ZFP64 (also known as ZNF338) is a member of the Krüppel C2H2-type zinc finger family. ZFP64 is a coactivator of Notch1, mediating mesenchymal cell differentiation. ZFP64 expression was up-regulated in mouse peritoneal macrophages in response to stimulation with the TLR4 ligand LPS with a 2-fold increase. The MLL gene encoding the MLL fusion protein is easily activated by ZFP64. ZFP64 is essential for the continuous production of MLL fusion proteins in blood cancer and produces more cancer cells. Since ZFP64 deletion completely and specifically inhibits MLL fusion protein production and leukemia cascade growth, it is an ideal drug target.
DPABH-01707 is suitable for use in Western blot (WB) (1:500–1:1,000) application.
DPABH-01707 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Zfp 64; ZFP64; Zinc finger protein 338; ZNF338

Entrez Gene ID

UniProt ID