KLH conjugated synthetic peptide corresponding to a region within C terminal amino acids 513-542 of Human ZBTB7A (NP_056982.1, UniProt ID: O95365).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/100 - 1/500.
Target
Alternative Names
ZBTB7A; zinc finger and BTB domain containing 7A; ZBTB7, zinc finger and BTB domain containing 7; zinc finger and BTB domain-containing protein 7A; DKFZp547O146; FBI 1; LRF; lymphoma related factor; pokemon; HIV 1 inducer of short transcripts binding prot
Plays a key role in the instruction of early lymphoid progenitors to develop into B lineage by repressing T-cell instructive Notch signals (By similarity). Specifically represses the transcription of the CDKN2A gene. Efficiently abrogates E2F1-dependent CDKN2A transactivation/de-repression. Binds to the consensus sequence 5-[GA][CA]GACCCCCCCCC-3.
Citations
Publication ()
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