Specifications
Immunogen
A synthetic peptide of human VPS45 is used for rabbit immunization.
Target
Alternative Names
VPS45; vacuolar protein sorting 45 homolog (S. cerevisiae); vacuolar protein sorting 45A (yeast homolog) , vacuolar protein sorting 45A (yeast) , VPS45A, VPS45B; vacuolar protein sorting-associated protein 45; h vps45; H1; hlVps45; vacuolar protein sortin
Product Background
Antigen Description
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators.
Pathway
Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem;
Citations
Publication ()
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