Anti-UNG monoclonal antibody (DCABH-822)

Mouse anti-Human UNG monoclonal antibody for WB, ICC/IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
3G4
Species Reactivity
Human
Immunogen
Recombinant full length Human UNG protein (NP_550433).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/2000; ICC/IF: 1/100;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
UNG; uracil-DNA glycosylase; DGU; HIGM4; UDG; UNG1
Entrez Gene ID
UniProt ID

Product Background


Pathway
Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Primary immunodeficiency, organism-specific biosystem; Primary immunodeficiency, conserved biosystem;

Citations


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References


Akbari, M; Otterlei, M; et al. Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells. NUCLEIC ACIDS RESEARCH 32:5486-5498(2004).
Perez-Duran, P; Belver, L; et al. UNG shapes the specificity of AID-induced somatic hypermutation. JOURNAL OF EXPERIMENTAL MEDICINE 209:1379-1389(2012).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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