Serine/threonine protein kinase which enhances GLI1 and GLI2 transcriptional activity and consequently positively regulates GLI-dependent SHH signaling. May exert this function by promoting GLI1 nuclear localization. Phosphorylates in vitro GLI2, as well as GLI1 and GLI3, although less efficiently.
Pathway
Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem; mTOR signaling pathway, organism-specific biosystem; mTOR signaling pathway, conserved biosystem;
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