Anti-UCP1 polyclonal antibody (DPABH-26313)

Rabbit anti-Human UCP1 (N-terminal) polyclonal antibody for ICC/IF, WB, IHC-P

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Mouse, Rat, Spermophilus tridecemlineatus
Immunogen
Synthetic peptide conjugated to KLH, corresponding to amino acids 145-159 of Human UCP1, with N-terminal cysteine added.
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 1/500; WB: 1/1000; IHC-P: 1/500.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
UCP1; uncoupling protein 1 (mitochondrial, proton carrier); UCP; mitochondrial brown fat uncoupling protein 1; SLC25A7; thermogenin
Entrez Gene ID
UniProt ID

Product Background


Pathway
Adipogenesis; Electron Transport Chain; Huntingtons disease; Metabolism; Mitochondrial Uncoupling Proteins; PPAR signaling pathway;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Sun, K; Asterholm, IW; et al. Dichotomous effects of VEGF-A on adipose tissue dysfunction. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 109:5874-5879(2012).
Ramadan, W; Marsili, A; et al. Type-2 Iodothyronine 5 ' Deiodinase (D2) in Skeletal Muscle of C57Bl/6 Mice. II. Evidence for a Role of D2 in the Hypermetabolism of Thyroid Hormone Receptor alpha-Deficient Mice. ENDOCRINOLOGY 152:3093-3102(2011).

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