Specifications
Species Reactivity
Human; Mouse; Rat; Cow; Pig; Horse; Guinea pig
Immunogen
KLH conjugated synthetic peptide derived from human PGP95: 35-140/223
Applications
Application Notes
IHC-P: 1:100-500
IHC-F: 1:100-500
IF: 1:100-500
General Notes
This product (Catalog No. DPABH-00846) is a rabbit-derived IgG polyclonal antibody raised against human UCHL1, targeting the amino acid region 35–140 of the protein. This antibody exhibits cross-reactivity with UCHL1 from mouse, rat, cow, pig, horse, and guineapig. It has been affinity purified by Protein A. The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.
DPABH-00846 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications.
DPABH-00846 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Target
Alternative Names
Gracile axonal dystrophy; Neuron cytoplasmic protein 9.5; Park 5; Park5; Parkinson Disease 5; PGP 9.5; PGP95; Protein gene product 9.5; Ubiquitin C terminal esterase L1; Ubiquitin C terminal hydrolase (neuron specific); Ubiquitin C terminal hydrolase; Ubiquitin carboxyl terminal esterase L1; Ubiquitin carboxyl terminal hydrolase isozyme L1; Ubiquitin carboxyl-terminal hydrolase isozyme L1; Ubiquitin thioesterase L1; Ubiquitin thiolesterase; Ubiquitin thiolesterase L1; UCH L1; UCH-L1; UCHL1; UCHL1_HUMAN
Citations
Publication ()
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