Rabbit Anti-Human UBE3C Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse

Immunogen

A synthesized peptide derived from human UBE3C.

Conjugate

Application Notes

IF/ICC 1:100-1:500

General Notes

This product (Catalog No. DPABH-12449) is a rabbit-derived polyclonal antibody raised against human UBE3C. This antibody exhibits cross-reactivity with UBE3C from mouse. It has been affinity purified by Protein A. E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
DPABH-12449 is suitable for use in IF/ICC 1 (100-1:500) application.
DPABH-12449 is supplied as a liquid formulation in Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Entrez Gene ID

UniProt ID