Anti-T. gondii SAG1 Monoclonal antibody (DMAB4413)

Mouse Anti-T. gondii SAG1 Monoclonal antibody for ELISA, IB, IF Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
C755M
Species Reactivity
T. gondii
Immunogen
Native T. gondii lysate
Conjugate
Unconjugated

Target


Alternative Names
Toxoplasma gondii SAG1; Major surface antigen; Surface antigen 1; Eukaryota; Chromalveolata; Alveolata

Product Background


Antigen Description
Toxoplasmais a crescent shaped sporozoan that lives as an intracellular parasite invarious tissues of many vertebrates and completes its life cycle in a singlehost. Its life cycle includes two phases called the intestinal (orenteroepithelial) and extraintestinal phases. The intestinal phase producesoocysts and occurs only in cats, wild as well as domesticated. Theextraintestinal phase occurs in all infected animals including cats, andproduces tachyzoites (actively proliferating trophozoites) and eventually,bradyzoites (slowly growing trophozoites) or zoitocysts. Infection due toToxoplasma gondii occurs in pregnant women where a variable degree ofimmunosuppression may exist or in patients receiving immunosuppressive drugtherapy. Toxoplasma infects tissue of the GI tract where an active infectionis accompanied by fever and enlargement of the spleen. Symptoms oftoxoplasmosis are generally mild but severe infection of lymph nodes mayoccur. Congenital toxoplasmosis, in which the maternal infection istransmitted during pregnancy, can produce blindness or mental retardation inthe newborn.

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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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