Anti-TUBB4B monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human TUBB4B is used for rabbit immunization.

Conjugate

Alternative Names

TUBB4B; tubulin, beta 4B class IVb; Beta2; TUBB2; TUBB2C; tubulin beta-4B chain; tubulin, beta 2C; tubulin, beta, 2; tubulin beta-2 chain; tubulin beta-2C chain; class IVb beta tubulin; class IVb beta-tubulin;

Entrez Gene ID

UniProt ID

Antigen Description

TUBB4B (tubulin, beta 4B class IVb) is a protein-coding gene. Diseases associated with TUBB4B include nasopharyngitis, and intrahepatic cholangiocarcinoma, and among its related super-pathways are Development Slit-Robo signaling and Proteolysis Role of Parkin in the Ubiquitin-Proteasomal Pathway. GO annotations related to this gene include structural molecule activity and GTP binding. An important paralog of this gene is LOC260334. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Pathway

Cell Cycle; Cell Cycle, Mitotic; Centrosome maturation; Chaperonin-mediated protein folding; Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding; Formation of tubulin folding intermediates by CCT/TriC; G2/M Transition; Gap junction; Loss of Nlp from mitotic centrosomes; Loss of proteins required for interphase microtubule organization??from the centrosome; Metabolism of proteins.