Magic™ Anti-TPH2 polyclonal antibody (CPBT-66759RR)

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Rat, Bovine, Human, Mouse, Zebrafish
Immunogen
Synthetic phospeptide corresponding to an amino acid sequence within TPH2, which includes phosphorylated Ser19.
Conjugate
Unconjugated

Applications


Application Notes
Western Blot: 1/1,000;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
TPH2; tryptophan hydroxylase 2; Ntph; tryptophan 5-hydroxylase 2; tryptophan 5-monooxygenase 2; neuronal tryptophan hydroxylase
Entrez Gene ID
UniProt ID
Q8CGU9

Product Background


Pathway
Amine-derived hormones; Melatonin biosynthesis, tryptophan => serotonin => melatonin; Metabolic pathways; Metabolism; Metabolism of amino acids and derivatives; Serotonergic synapse; Serotonin and melatonin biosynthesis; Tryptophan metabolism;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Adori, C; Ando, RD; et al. Recovery and Aging of Serotonergic Fibers After Single and Intermittent MDMA Treatment in Dark Agouti Rat. JOURNAL OF COMPARATIVE NEUROLOGY 519:2353-2378(2011).
Manjarrez-Gutierrez, G; Martinez-Radilla, K; et al. Increased expression of tryptophan-5-hydroxylase 1, but not 2, in brainstem as a result of intrauterine malnutrition. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE 30:445-450(2012).

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