Synthetic peptide within Human MURF1 aa 2-14. The exact sequence is proprietary. (NP_115977)Sequence: DYKSSLIQDGNPM Database link: Q969Q1
Conjugate
Unconjugated
Applications
Application Notes
IHC-P: 1/25 - 1/100; WB: 1/1000 - 1/5000;
Target
Alternative Names
TRIM63; tripartite motif containing 63, E3 ubiquitin protein ligase; IRF; SMRZ; MURF1; MURF2; RNF28; E3 ubiquitin-protein ligase TRIM63; ring finger protein 28; iris ring finger protein; muscle specific ring finger protein 2; muscle-specific RING finger p
E3 ubiquitin ligase. Regulates proteasomal degradation of cardiac troponin I/TNNI3 and probably of other sarcomeric-associated proteins. May play a role in striated muscle atrophy and hypertrophy by regulating an anti-hypertrophic PKC-mediated signaling pathway. May regulate the organization of myofibrils through TTN in muscle cells.
Pathway
Adaptive Immune System; Class I MHC mediated antigen processing & presentation; TWEAK Signaling Pathway;
Citations
Publication ()
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COA
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