Synthetic peptide within Human Tropomyosin 2 aa 251-280 (C terminal) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary.Database link: P07951
Conjugate
Unconjugated
Applications
Application Notes
WB: 1/100 - 1/500;
Target
Alternative Names
TPM2; tropomyosin 2 (beta); DA1; DA2B; NEM4; TMSB; AMCD1; HEL-S-273; tropomyosin beta chain; nemaline myopathy type 4; epididymis secretory protein Li 273;
Binds to actin filaments in muscle and non-muscle cells. Plays a central role, in association with the troponin complex, in the calcium dependent regulation of vertebrate striated muscle contraction. Smooth muscle contraction is regulated by interaction with caldesmon. In non-muscle cells is implicated in stabilizing cytoskeleton actin filaments. The non-muscle isoform may have a role in agonist-mediated receptor internalization.
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