Anti-TPM2 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human TPM2 is used for rabbit immunization.

Conjugate

Alternative Names

TPM2; tropomyosin 2 (beta); AMCD1, arthrogryposis multiplex congenital, distal, type 1; tropomyosin beta chain; DA1; tropomyosin-2; DA2B; NEM4; TMSB; AMCD1;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes beta-tropomyosin, a member of the actin filament binding protein family, and mainly expressed in slow, type 1 muscle fibers. Mutations in this gene can alter the expression of other sarcomeric tropomyosin proteins, and cause cap disease, nemaline myopathy and distal arthrogryposis syndromes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene

Pathway

Cardiac muscle contraction, organism-specific biosystem; Cardiac muscle contraction, conserved biosystem; Dilated cardiomyopathy, organism-specific biosystem; Dilated cardiomyopathy, conserved biosystem; Hypertrophic cardiomyopathy (HCM), organism-specific biosystem; Hypertrophic cardiomyopathy (HCM), conserved biosystem; Muscle contraction, organism-specific biosystem;