Rabbit Anti-Human TONSL (C-terminal) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Fusion protein corresponding to residues near the C terminal of human tonsoku-like, DNA repair protein

Conjugate

Application Notes

IHC: 1:100-1:300

General Notes

This product (Catalog No. DPABH-07197) is a rabbit-derived IgG polyclonal antibody raised against human TONSL. It has been affinity purified by protein A. The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
DPABH-07197 is suitable for use in IHC (1:100–1:300) application.
DPABH-07197 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

IKBR; NFKBIL2

Entrez Gene ID

UniProt ID