Rabbit Anti-Human TMPRSS11D (a.a. 21-120) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

KLH conjugated synthetic peptide derived from human TMPRSS11D: 21-120/418

Conjugate

Application Notes

IHC-P: 1:100-500
IHC-F: 1:100-500
IF: 1:100-500

General Notes

This product (Catalog No. DPABH-23107) is a rabbit-derived IgG polyclonal antibody raised against human TMPRSS11D, targeting the amino acid region 21–120 of the protein. It has been affinity purified by Protein A. This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38% identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. This protein facilitates entry of viruses into host cells by proteolytically cleaving and activating viral envelope glycoproteins.
DPABH-23107 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications.
DPABH-23107 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Airway trypsin like protease; Airway trypsin-like protease; HAT; MGC150587; MGC150588; TM11D_HUMAN; TMPRSS11D; Transmembrane protease serine 11D; Transmembrane protease serine 11D catalytic chain; Transmembrane protease serine 11D precursor

Entrez Gene ID

UniProt ID