Anti-TMEM55B polyclonal antibody (DPABH-23810)

Rabbit anti-Human TMEM55B (aa 182-211) polyclonal antibody for WB, IHC-P


Host Species
Antibody Isotype
Species Reactivity
Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 182-211 of Human TM55B (NP_001094284.1, NP_653169.2).


Application Notes
WB: 1/100 - 1/500. IHC-P: 1/10 - 1/50.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.


Alternative Names
TMEM55B; transmembrane protein 55B; C14orf9; type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase; ptdIns-4,5-P2 4-Ptase I; type 1 PtdIns-4,5-P2 4-Ptase
Entrez Gene ID
UniProt ID

Product Background

Gene summary
TMEM55B (Transmembrane Protein 55B) is a Protein Coding gene. Among its related pathways are Inositol phosphate metabolism (KEGG) and 3-phosphoinositide degradation. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is TMEM55A. TMEM55B catalyzes the degradation of phosphatidylinositol 4,5-bisphosphate (PtdIns-4,5-P2) by removing the 4-phosphate (Ungewickell et al. , 2005 [PubMed 16365287]).
Antigen Description
Catalyzes the hydrolysis of the 4-position phosphate of phosphatidylinositol 4,5-bisphosphate. Does not hydrolyze phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 3,4-bisphosphate, inositol 3,5-bisphosphate, inositol 3,4-bisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate. The function about TMEM55B antigen include hydrolase activity.
3-phosphoinositide degradation; D-myo-inositol-5-phosphate metabolism; superpathway of inositol phosphate compounds.


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Medina, MW; Bauzon, F; et al. Transmembrane Protein 55B Is a Novel Regulator of Cellular Cholesterol Metabolism. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 34:1917-1923(2014).

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