Specifications
Immunogen
Full length protein corresponding to Human TLR1. Fused to the Fc portion of Human IgG1.Database link: Q15399
Applications
Application Notes
IHC-Fr: 1/50; IHC-P: 1/50.
Target
Alternative Names
TLR1; toll-like receptor 1; CD281; KIAA0012; rsc786; toll/interleukin-1 receptor-like protein; TIL; TIL. LPRS5; MGC104956; MGC126311; MGC126312; DKFZp547I0610; DKFZp564I0682;
Product Background
Antigen Description
Participates in the innate immune response to microbial agents. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.
Pathway
Activated TLR4 signalling, organism-specific biosystem; Beta defensins, organism-specific biosystem; Defensins, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88:Mal cascade initiated on plasma membrane, organism-specific biosystem; Toll Like Receptor 2 (TLR2) Cascade, organism-specific biosystem;
Citations
Publication ()
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COA
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