Anti-TINCR polyclonal antibody (DPABH-22226)

Rabbit anti-Human TINCR (N-terminal) polyclonal antibody for ICC/IF, WB Datasheet

Online Inquiry Add to basket

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
17 amino acid synthetic peptide near the center of Human PLAC2 (AAQ15237).
Conjugate
Unconjugated

Applications


Application Notes
ICC/IF: 20 μg/ml. WB: 1 - 2 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
TINCR; tissue differentiation-inducing non-protein coding RNA; PLAC2; LINC00036; NCRNA00036
Entrez Gene ID

Product Background


Gene summary
TINCR (Tissue Differentiation-Inducing Non-Protein Coding RNA) is an RNA Gene, and is affiliated with the non-coding RNA class. This gene produces a spliced long non-coding RNA that is required for normal epidermal differentiation. This transcript regulates the expression of genes involved in the differentiation of epidermal tissue. Mutations in some of the genes targeted by this transcript have been implicated in epidermal skin diseases.
Antigen Description
This locus is inferred to be non-protein-coding based on the observations that a) there is no homology support for predicted open reading frames; and b) the location of the longer predicted open reading frame renders the transcript a candidate for nonsense-mediated decay (NMD) as the stop codon is >50 nucleotides upstream of the terminal splice site.

Citations


Have you cited DPABH-22226 in a publication? Let us know and earn a reward for your research.

References


Kretz, M; et al. TINCR, staufen1, and cellular differentiation. RNA BIOLOGY 10:1597-1601(2013).
Kretz, M; Siprashvili, Z; et al. Control of somatic tissue differentiation by the long non-coding RNA TINCR. NATURE 493:231-U245(2013).

Related Products


Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !

Online Inquiry

Name
Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: Anti-TINCR polyclonal antibody

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket