Anti-TINCR polyclonal antibody (DPABH-22226)

Rabbit anti-Human TINCR (N-terminal) polyclonal antibody for ICC/IF, WB Datasheet

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Host Species
Antibody Isotype
Species Reactivity
17 amino acid synthetic peptide near the center of Human PLAC2 (AAQ15237).


Application Notes
ICC/IF: 20 μg/ml. WB: 1 - 2 μg/ml.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.


Alternative Names
TINCR; tissue differentiation-inducing non-protein coding RNA; PLAC2; LINC00036; NCRNA00036
Entrez Gene ID

Product Background

Gene summary
TINCR (Tissue Differentiation-Inducing Non-Protein Coding RNA) is an RNA Gene, and is affiliated with the non-coding RNA class. This gene produces a spliced long non-coding RNA that is required for normal epidermal differentiation. This transcript regulates the expression of genes involved in the differentiation of epidermal tissue. Mutations in some of the genes targeted by this transcript have been implicated in epidermal skin diseases.
Antigen Description
This locus is inferred to be non-protein-coding based on the observations that a) there is no homology support for predicted open reading frames; and b) the location of the longer predicted open reading frame renders the transcript a candidate for nonsense-mediated decay (NMD) as the stop codon is >50 nucleotides upstream of the terminal splice site.


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Kretz, M; Siprashvili, Z; et al. Control of somatic tissue differentiation by the long non-coding RNA TINCR. NATURE 493:231-U245(2013).
Bakker, JF; Paulides, MM; et al. Children and adults exposed to electromagnetic fields at the ICNIRP reference levels: theoretical assessment of the induced peak temperature increase. PHYSICS IN MEDICINE AND BIOLOGY 56:4967-4989(2011).

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