Anti-TFCP2 (aa 414-502) polyclonal antibody

Species Reactivity

Human

Immunogen

TFCP2 (AAH03634, 414 a.a. ~ 502 a.a) partial recombinant protein with GST tag. The sequence is KHEDGDSNGTFFVYHAIYLEELTAVELTEKIAQLFSISPCQISQIYKQGPTGIHVLISDE MIQNFQEEACFILDTMKAETNDSYHIILK

Conjugate

Alternative Names

TFCP2; transcription factor CP2; LSF; SEF; LBP1C; LSF1D; TFCP2C; alpha-globin transcription factor CP2; SAA3 enhancer factor;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a transcription factor that binds the alpha-globin promoter and activates transcription of the alpha-globin gene. The encoded protein regulates erythroid gene expression, plays a role in the transcriptional switch of globin gene promoters, and it activates many other cellular and viral gene promoters. The gene product interacts with certain inflammatory response factors, and polymorphisms of this gene may be involved in the pathogenesis of Alzheimers disease.

Pathway

Signaling events mediated by HDAC Class I;