Anti-TFAP2A (aa 99-205) polyclonal antibody

Species Reactivity

Human

Immunogen

TFAP2A (AAH17754, 99 a.a. ~ 205 a.a) partial recombinant protein with GST tag. The sequence is SGLLHTHRGLPHQLSGLDPRRDYRRHEDLLHGPHALSSGLGDLSIHSLPHAIEEVPHVED PGINIPDQTVIKKGPVSLSKSNSNAVSAIPINKDNLFGGVVNPNEVF

Conjugate

Alternative Names

TFAP2A; transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha); AP-2; BOFS; AP2TF; TFAP2; AP-2alpha; transcription factor AP-2-alpha; AP2-alpha; activator protein 2; AP-2 transcription factor; activating enhancer-binding protein 2-a

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a transcription factor that binds the consensus sequence 5-GCCNNNGGC-3. The encoded protein functions as either a homodimer or as a heterodimer with similar family members. This protein activates the transcription of some genes while inhibiting the transcription of others. Defects in this gene are a cause of branchiooculofacial syndrome (BOFS). Three transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Dec 2009]

Pathway

Caspase cascade in apoptosis; Neural Crest Differentiation;