Anti-TDO2 monoclonal antibody (CAB-4838MH)

Mouse anti-TDO2 monoclonal antibody for ELISA Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG2a
Clone
2D9
Species Reactivity
Human
Immunogen
TDO2 (NP_005642, 307 a.a. - 406 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Conjugate
Unconjugated

Target


Alternative Names
TDO2; tryptophan 2,3-dioxygenase; TDO; TPH2; tryptophanase; tryptophan oxygenase
Entrez Gene ID
UniProt ID

Product Background


Pathway
Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Monoamine Transport, organism-specific biosystem; NAD biosynthesis II (from tryptophan), organism-specific biosystem; NAD biosynthesis II (from tryptophan), conserved biosystem; Tryptophan catabolism, organism-specific biosystem;

Citations


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References


Vasil'ev, GV; Merkulov, VM; et al. Point mutations at positions 663 and 666 associated with mental disorders alter the binding site for transcription factor YY1 in the human tryptophan dioxygenase gene intron 6. MOLECULAR BIOLOGY 34:186-193(2000).
Ponomarenko, J; Orlova, G; et al. Mining genome variation to associate genetic disease with mutation alterations and ortho/paralogous polimorphysms in transcription factor binding site. INTERNATIONAL JOURNAL ON ARTIFICIAL INTELLIGENCE TOOLS 14:599-619(2005).

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