Anti-TBP (aa 1-100) polyclonal antibody

Name: Anti-TBP (aa 1-100) polyclonal antibody
SKU: DPABH-16889
Rating: 5 (1 reviews)

Rabbit Anti-Human TBP (aa 1-100) polyclonal for ICC/IF; IP; ChIP; IHC-P; WB

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COA

SDS

Datasheet

Summary

Specifications

Antibody Isotype

IgG

Species Reactivity

Mouse; Rat; Human

Immunogen

Synthetic peptide conjugated to KLH derived from within residues 1 - 100 of Human TATA binding protein TBP.

Conjugate

Unconjugated

Applications

Application Notes

ICC/IF: 1/500; ChIP: 5 μg for 25 of chromatin; IHC-P: 10 μg/ml; WB: 1 μg/ml;

Target

Alternative Names

TATA box binding protein;TFIID;Transcription initiation factor TFIID TBP subunit;GTF2D1;TATA sequence-binding protein;TATA-box binding protein N-terminal domain;TATA-box factor;TATA-box-binding protein;HDL4;TF2D;SCA17;TATA-binding factor;GTF2D;TBP_HUMAN;

Entrez Gene ID

6908

UniProt ID

P20226

Product Background

Antigen Description

General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

Pathway

Basal transcription factors; Disease; Epstein-Barr virus infection; Eukaryotic Transcription Initiation

Citations

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Documents

pdf COA

pdf SDS

pdf Datasheet

QA & Reviews

Customer Reviews

References

Bandwidth optimization and side-lobe levels reduction in PC radar using Legendre orthogonal polynomials

DIGITAL SIGNAL PROCESSING

Authors: Thakur, Ankur; Saini, Davinder Singh

Abstract

Time-bandwidth product (TBP), peak side-lobe level (PSL), integrated side-lobe level (ISL), and relative main-lobe width are considered important performance parameters in pulse compression (PC) radar for the selection of transmitting waveforms. In radar system, linear frequency modulated (LFM) waveforms are popular for transmission. LFM waveforms suffer from the range side-lobes problem which affects accurate detection of the target. This paper describes a new transmitting waveform based on Legendre orthogonal polynomial (LOP) for bandwidth optimization and side-lobe levels reduction in PC radar. PC provides the benefits of long duration pulse for better range resolution and detection. Different order LOPs are examined with varying optimizing parameter (gamma), and the polynomial giving optimum performance is chosen. Further, different windowing methods are added in cascade to decrease the side-lobes but with the limitation of wider relative main-lobe width. Simulation results indicate that the proposed LOP gives better side-lobe reduction than LFM and Chebyshev chaotic sequences. (C) 2020 Elsevier Inc. All rights reserved.

Revealing the Mechanism of Doping of spiro-MeOTAD via Zn Complexation in the Absence of Oxygen and Light

ACS ENERGY LETTERS

Authors: Saygili, Yasemin; Kim, Hui-Seon; Yang, Bowen; Suo, Jiajia; Munoz-Garcia, Ana B.; Pavone, Michele; Hagfeldt, Anders

Abstract

In this study, a new mechanism for doping of spiro-MeOTAD by Zn(TFSI)(2) is revealed, which is completely different from the mechanism induced by LiTFSI. The oxidation of spiro-MeOTAD is facilitated by complexation between the zinc cation and tert-butylpyridine (tBP) even in the absence of oxygen and light. The lone electron pair of nitrogen in tBP coordinates to the zinc cation, confirmed by the Fourier transform infrared spectroscopy peak at 1637 cm(-1) corresponding to a pyridine ring mode coupled with nitrogen coordinating to zinc as the Lewis site. The doping mechanism is also evidenced by computational calculations. The coordination of zinc to tBP and TFSI- provides a driving force and stabilizes the oxidized spiro-MeOTAD species, showing the most favorable reaction by forming a [Zn(tBP)(3)](+)(TFSI-) complex with a Delta E of -1.52 eV. Our discovery of the mechanism of doping by Zn(TFSI)(2) provides practical insight for the oxidation of spiro-MeOTAD by avoiding ambiguous aging processes in ambient or dry air at the risk of decomposition of other components.