General Notes
This product (Catalog No. DPABH-15200) is a rabbit-derived IgG polyclonal antibody raised against human TAX1BP1, targeting the amino acid region 241–340 of the protein. This antibody exhibits cross-reactivity with TAX1BP1 from mouse, rat, dog, cow, horse, and sheep. It has been affinity purified by Protein A. This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
DPABH-15200 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications.
DPABH-15200 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
Alternative Names
1200003J11Rik; 1700069J21Rik; Aa1076; AA930106; CALCOCO 3; CALCOCO3; D6Ertd404e; D6Ertd772e; Human T cell leukemia virus type 1-binding protein; Liver regeneration-related protein LRRG004; MGC94031; PRO0105; T6BP; Tax1 (human T cell leukemia virus type I) binding protein 1; Tax1 (human T cell leukemia virus type I) binding protein; Tax1 binding protein 1; Tax1 binding protein; Tax1-binding protein 1; Tax1-binding protein 1 homolog; TAX1BP1; TAX1BP1 protein; tax1bp1b; TAXB1_HUMAN; TRAF 6 binding protein; TRAF6 binding protein; TRAF6 binding protein T6BP; TRAF6-binding protein; TRAF6-interacting protein; TXBP 151; TXBP151; wu:fc20c12; wu:fc56e11; zgc:73219; zgc:77129