Anti-TAS2R31 polyclonal antibody (DPABH-24019)

Rabbit Anti-Human TAS2R31 (aa 279-309) polyclonal antibody for WB

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
KLH conjugated synthetic peptide corresponding to a region within C terminal amino acids 279-309 of Human TAS2R44 (NP_795366.2).
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/100 - 1/500.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
TAS2R31; taste receptor, type 2, member 31; T2R31; T2R44; T2R53; TAS2R44
Entrez Gene ID
UniProt ID

Product Background


Gene summary
TAS2R31 (Taste 2 Receptor Member 31) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity and bitter taste receptor activity. An important paralog of this gene is TAS2R42. TAS2R44 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al. , 2002 [PubMed 12584440]). For further information on TAS2Rs, see MIM 604791.
Antigen Description
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). Activated by the sulfonyl amide sweeteners saccharin and acesulfame K. Taste receptor, type 2, member 31, also known as TAS2R31, is a protein which in humans is encoded by the TAS2R31 gene. This bitter taste receptor has been shown to respond to saccharin in vitro. 0The function about TAS2R31 antigen include bitter taste receptor activity.
Pathway
Class C/3 (Metabotropic glutamate/pheromone receptors); GPCR downstream signaling; Signal Transduction; Taste transduction.

Citations


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We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Roudnitzky, N; Bufe, B; et al. Genomic, genetic and functional dissection of bitter taste responses to artificial sweeteners. HUMAN MOLECULAR GENETICS 20:3437-3449(2011).
Hayes, JE; Feeney, EL; et al. Do polymorphisms in chemosensory genes matter for human ingestive behavior?. FOOD QUALITY AND PREFERENCE 30:202-216(2013).

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