Anti-TAS1R1 (aa 281-380) polyclonal antibody

Species Reactivity

Human

Immunogen

TAS1R1 (NP_619642, 281 a.a. ~ 380 a.a) partial recombinant protein with GST tag. The sequence is RVFFESVVLTNLTGKVWVASEAWALSRHITGVPGIQRIGMVLGVAIQKRAVPGLKAFEEA YARADKEAPRPCHKGSWCSSNQLCRECQAFMAHTMPKLKA

Conjugate

Alternative Names

TAS1R1; taste receptor, type 1, member 1; TR1; T1R1; GM148; GPR70; taste receptor type 1 member 1; G protein-coupled receptor 70; G-protein coupled receptor 70; seven transmembrane helix receptor;

Entrez Gene ID

UniProt ID

Antigen Description

The protein encoded by this gene is a G protein-coupled receptor and is a component of the heterodimeric amino acid taste receptor T1R1+3. The T1R1+3 receptor responds to L-amino acids but not to D-enantiomers or other compounds. Most amino acids that are perceived as sweet activate T1R1+3, and this activation is strictly dependent on an intact T1R1+3 heterodimer. Multiple transcript variants encoding different isoforms have been found for this gene.

Pathway

Class C/3 (Metabotropic glutamate/pheromone receptors); Signal Transduction; Taste transduction;