Thiol activated cytolysin; Slo; Streptolysin O; Thiol activated cytolysin; SLO; Hemolysins O, Streptococcus group A; Eubacteria; Firmicutes; Cocci; Lactobacillales; Streptococcaceae; Streptococcus; S. pyogenes; Streptococcus pyogenes
Product Background
Antigen Description
Streptolysin O (SLO) is a membrane-damaging extracellular toxin produced by hemolytic streptococci. In the hemolytic streptococci infection, the antibodies to various proteins secreted from the bacteria such as toxins increase. For the diagnostic confirmation of the hemolytic streptococci infection, measurement of the antibody, ASLO (Anti-Streptolysin O), is most widely used. The antibody was prepared by immunizing rabbit with the purified recombinant SL0 of Group C hemolytic streptococci expressed in E. coli. Using this antiserum it is possible to detect not only hemolytic streptolysin 0 of Group A origin but also of Group C and G.
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