Anti-SLC6A3 monoclonal antibody (DCABH-2865)

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
FQS8974
Species Reactivity
Human
Immunogen
Synthetic peptide corresponding to residues in the extracellular domain of Human Dopamine Transporter.
Conjugate
Unconjugated

Applications


Application Notes
IP: 1/10 - 1/100; WB: 1/10000 - 1/50000; Flow Cyt: 1/10 - 1/100.
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SLC6A3; solute carrier family 6 (neurotransmitter transporter, dopamine), member 3; DAT1; sodium-dependent dopamine transporter; DAT; dopamine transporter
Entrez Gene ID
UniProt ID

Product Background


Pathway
Alpha-synuclein signaling, organism-specific biosystem; Amphetamine addiction, organism-specific biosystem; Amphetamine addiction, conserved biosystem; Cocaine addiction, organism-specific biosystem; Cocaine addiction, conserved biosystem; Dopamine clearance from the synaptic cleft, organism-specific biosystem; Dopaminergic synapse, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Metzler, R; Meleshkevitch, EA; et al. An SLC6 transporter of the novel B-0,B-- system aids in absorption and detection of nutrient amino acids in Caenorhabditis elegans. JOURNAL OF EXPERIMENTAL BIOLOGY 216:2843-2857(2013).
Takayama, H; Sugio, S; et al. Functional expression of milligram quantities of the synthetic human serotonin transporter gene in a tetracycline-inducible HEK293 cell line. PROTEIN EXPRESSION AND PURIFICATION 76:211-220(2011).

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