Anti-GAL4 monoclonal antibody (CABT-30498MS)

Mouse anti-Saccharomyces cerevisiae GAL4 monoclonal antibody for ELISA, ICC/IF, WB Datasheet

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Specifications


Host Species
Mouse
Antibody Isotype
IgG1
Clone
4H263
Species Reactivity
S. cerevisiae
Immunogen
Recombinant fragment, corresponding to amino acids 1-147 of S. cerevisiae GAL4.
Conjugate
Unconjugated

Applications


Application Notes
ELISA: 0.1 - 1μg/ml; WB: 3μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
GAL4; Gal4p; Antigen NY CO 27; Antigen NYCO27; GAL 4; Galectin 4
Entrez Gene ID
UniProt ID

Product Background


Gene summary
LGALS4 (Lectin, Galactoside Binding Soluble 4) is a Protein Coding gene. Diseases associated with LGALS4 include colorectal cancer and paraneoplastic cerebellar degeneration. Among its related pathways are Cell adhesion_Cell-matrix glycoconjugates. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is LGALS9B. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. The expression of this gene is restricted to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer.
Antigen Description
This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions. Galectin-4 is a protein that in humans is encoded by the LGALS4 gene. 0The function about GAL4 antigen include DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA p.

Citations


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References


Hayashida, T; Poncelet, AC; et al. TGF-beta 1 activates MAP kinase in human mesangial cells: A possible role in collagen expression. KIDNEY INTERNATIONAL 56:1710-1720(1999).
Nguyen, TTA; Nishitani, M; et al. Essential Role of Duox in Stabilization of Drosophila Wing. JOURNAL OF BIOLOGICAL CHEMISTRY 286:33244-33251(2011).

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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