General Notes
This product (Catalog No. DPABH-05994) is a rabbit-derived polyclonal antibody raised against human SYT17, targeting the amino acid region 127–474 of the protein. This antibody exhibits cross-reactivity with Human SYT17 from mouse and rat. It has been affinity purified by Protein A. SYT17, or synaptotagmin 17, is a protein that belongs to the synaptotagmin family, which is known for its role in regulating exocytosis at the plasma membrane. Reports find high levels of expression in hippocampus, particularly in pyramidal cell layers and in cultured hippocampal neurons. SYT17 is thus a multifunctional regulator of intracellular protein trafficking in excitatory hippocampal neurons, modulating both neural development and synaptic physiology. (PMID: 31387992, PMID: 36332665).
DPABH-05994 is suitable for use in IHC (1:20–1:200), IF/ICC (1:200–1:800) applications.
DPABH-05994 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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