Anti-SUCNR1 polyclonal antibody (DPABH-02456)

Rabbit anti-Human SUCNR1 (cytoplasmic domain) polyclonal antibody for IHC-P

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Species Reactivity
Human
Immunogen
Synthetic 15 amino acid peptide from the 2nd cytoplasmic domain of Human GPR91.
Conjugate
Unconjugated

Applications


Application Notes
IHC-P: 3 μg/ml;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
SUCNR1; succinate receptor 1; GPR91; P2Y purinoceptor 1; G protein-coupled receptor 91; G-protein coupled receptor 91
Entrez Gene ID
UniProt ID

Product Background


Gene summary
SUCNR1 (Succinate Receptor 1) is a Protein Coding gene. Diseases associated with SUCNR1 include exudative vitreoretinopathy 1. Among its related pathways are Signaling by GPCR and cAMP signaling pathway. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is P2RY2. This gene encodes a G-protein-coupled receptor for succinate, an intermediate molecule of the citric acid cycle. It is involved in the promotion of hematopoietic progenitor cell development, and it has a potential role in renovascular hypertension which has known correlations to renal failure, diabetes and atherosclerosis.
Antigen Description
Receptor for succinate. Succinate receptor 1 is a protein that in humans is encoded by the SUCNR1 gene. 0The function about SUCNR1 antigen include G-protein coupled receptor activity.
Pathway
Class A/1 (Rhodopsin-like receptors); GPCR downstream signaling; GPCRs, Class A Rhodopsin-like; Signaling by GPCR.

Citations


Have you cited DPABH-02456 in a publication? Let us know and earn a reward for your research.

Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

Customer Reviews


Write a review, share your experiences with others and get rewarded !
Product Name Cat. No. Applications Host Species Datasheet Price Add to Basket

References


Bayes, M; Rabasseda, X; et al. Gateways to clinical trials - January/February 2003. METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY 25:53-76(2003).
Turley, JM; Fu, T; et al. Vitamin E succinate induces Fas-mediated apoptosis in estrogen receptor-negative human breast cancer cells. CANCER RESEARCH 57:881-890(1997).

Online Inquiry

Name:
Phone: *
E-mail Address: *
Service & Products Interested: *
Project Description:
Verification Code: * Please input "diagnostics" as verification code.

Online Inquiry

  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket