Anti-STAT3 monoclonal antibody (DCABH-8572) Knockout Validated

Rabbit anti-Human STAT3 monoclonal antibody for IHC-Fr, WB, IHC-P, IP

Specifications


Host Species
Rabbit
Antibody Isotype
IgG
Clone
F232-32
Species Reactivity
Human
Immunogen
A synthetic peptide corresponding to residues surrounding Ser727 of human Stat3.
Conjugate
Unconjugated

Applications


Application Notes
WB: 1/1000; IP: 1/20;
*Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Target


Alternative Names
STAT3; signal transducer and activator of transcription 3 (acute-phase response factor); signal transducer and activator of transcription 3; APRF; DNA-binding protein APRF; acute-phase response factor
Entrez Gene ID
UniProt ID

Product Background


Pathway
Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem;

Citations


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Custom Antibody Labeling


We offer labeled antibodies using our catalogue antibody products and a broad range of intensely fluorescent dyes and labels including HRP, biotin, ALP, Alexa Fluor® dyes, DyLight® Fluor dyes, R-phycoerythrin (R-PE), at scales from less than 100 μg up to 1 g of IgG antibody. Learn More

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References


Muthu, K; Panneerselvam, M; et al. Structural perspective of ARHI mediated inhibition of STAT3 signaling: An insight into the inactive to active transition of ARHI and its interaction with STAT3 and importin beta. CELLULAR SIGNALLING 27:739-755(2015).
Sun, Y; Lehmbecker, A; et al. STAT3 represents a molecular switch possibly inducing astroglial instead of oligodendroglial differentiation of oligodendroglial progenitor cells in Theiler's murine encephalomyelitis. NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY 41:347-370(2015).

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