Anti-ST3GAL3 monoclonal antibody, clone FQS21117(3)

Antibody Isotype

IgG

Clone

FQS21117(3)

Species Reactivity

Mouse; Rat; Human

Conjugate

Application Notes

IHC-P: 1/250 - 1/500; WB: 1/1000 - 1/10000; ICC/IF: 1/50 - 1/100; Flow Cyt: 1/10 - 1/100.

Alternative Names

ST3GAL3; ST3 beta-galactoside alpha-2,3-sialyltransferase 3; sialyltransferase 6 (N acetyllacosaminide alpha 2,3 sialyltransferase) , SIAT6; CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; ST3Gal III; alpha 2,3-ST 3; alpha-2,3-si

Entrez Gene ID

UniProt ID

Antigen Description

ST3GAL3 is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. It is normally found in the Golgi apparatus but can be proteolytically processed to a soluble form. It is a member of glycosyltransferase family 29. Multiple transcript variants encoding several different isoforms have been found for this gene.

Pathway

Glycosaminoglycan biosynthesis - keratan sulfate, organism-specific biosystem; Glycosaminoglycan biosynthesis - keratan sulfate, conserved biosystem; Glycosphingolipid biosynthesis - lacto and neolacto series, organism-specific biosystem; Glycosphingolipid biosynthesis - lacto and neolacto series, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; O-linked glycosylation of mucins, organism-specific biosystem;