Anti-SNX9 monoclonal antibody, clone 4D7

Antibody Isotype

IgG2b

Clone

4D7

Species Reactivity

Human

Immunogen

SNX9 (AAH05022, 1 a.a. ~ 595 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Conjugate

Alternative Names

SNX9; sorting nexin 9; sorting nexin-9; SDP1; SH3PX1; SH3PXD3A; SH3 and PX domain-containing protein 1; SH3 and PX domain-containing protein 3A; SH3 and PX domain-containing protein SH3PX1; Wiskott-Aldrich syndrome protein (WASP) interactor protein; WISP;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but does contain a SH3 domain near its N-terminus. This protein interacts with the cytoplasmic domains of the precursor but not the processed forms of a disintegrin and metalloprotease domain 9 and 15. This protein binds the beta-appendage domain of adaptor protein 2 and may function to assist adaptor protein 2 in its role at the plasma membrane. This protein interacts with activated Cdc42-associated kinase-2 to regulate the degradation of epidermal growth factor receptor protein.

Pathway

Clathrin derived vesicle budding, organism-specific biosystem; Golgi Associated Vesicle Biogenesis, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; trans-Golgi Network Vesicle Budding, organism-specific biosystem;