a 14 amino acid peptide near the amino-terminus of the human Slc35D1.
Conjugate
Unconjugated
Target
Alternative Names
SLC35D1; solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1; UGTREL7; UDP-glucuronic acid/UDP-N-acetylgalactosamine transporter; UDP-GlcA/UDP-GalNAc transporter; solute carrier family 35 member D1; UDP-galactose transporter-related 7; U
Glycosylation of cellular glycoconjugates occurs in the endoplasmic reticulum (ER) and Golgi compartment, and requires transport of nucleotide sugars from the cytosol into the lumen of the ER and Golgi by specific transporters. The protein encoded by this gene resides in the ER, and transports both UDP-glucuronic acid (UDP-GlcA) and UDP-N-acetylgalactosamine (UDP-GalNAc) from the cytoplasm to the ER lumen. It may participate in glucuronidation and/or chondroitin sulfate biosynthesis. Mutations in this gene are associated with Schneckenbecken dysplasia.[provided by RefSeq, Sep 2009]
Pathway
Biological oxidations; Formation of the active cofactor; Glucuronidation; Metabolism; Phase II conjugation; SLC-mediated transmembrane transport; Transmembrane transport of small molecules; Transport of nucleotide sugars
Citations
Publication ()
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COA
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