Specifications
Immunogen
A synthetic peptide of human SLC35B2 is used for rabbit immunization.
Target
Alternative Names
SLC35B2; solute carrier family 35, member B2; adenosine 3-phospho 5-phosphosulfate transporter 1; UGTrel4; PAPS transporter 1; putative MAPK-activating protein PM15; putative NF-kappa-B-activating protein 48; solute carrier family 35 member B2 variant 2;
Product Background
Antigen Description
Sulfotransferases (e.g., SULT4A1; MIM 608359) use an activated form of sulfate, 3-prime-phosphoadenosine 5-prime-phosphosulfate (PAPS), as a common sulfate donor for sulfation of glycoproteins, proteoglycans, and glycolipids in the endoplasmic reticulum and Golgi apparatus. SLC35B2 is located in the microsomal membrane and transports PAPS from the cytosol, where it is synthesized, into the Golgi lumen (Kamiyama et al., 2003 [PubMed 12716889]).
Pathway
SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosystem; Transport of nucleotide sugars, organism-specific biosystem; Transport of vitamins, nucleosides, and related molecules, organism-specific biosystem;
Citations
Publication ()
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