Synthetic peptide corresponding to a region within internal sequence amino acids 180-229 (HYEIANSPEE AISLAKTTFD EAMADLHTLS EDSYKDSTLI MQLLRDNLTL) of Human 14-3-3 sigma (NP_006133).
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml; IHC-P: 2.5 μg/ml;
Target
Alternative Names
SFN; stratifin; YWHAS; 14-3-3 protein sigma; 14-3-3 sigma; epithelial cell marker protein 1;
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway.p53-regulated inhibitor of G2/M progression.
Pathway
Activation of BAD and translocation to mitochondria; Aldosterone-regulated sodium reabsorption; Alpha6-Beta4 Integrin Signaling Pathway; Calcium Regulation in the Cardiac Cell
Citations
Publication ()
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COA
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