Rabbit Anti-Human SAP62 (a.a. 65-160) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse; Human; Rat; Chicken; Dog; Cow

Immunogen

KLH conjugated synthetic peptide derived from human SAP62: 65-160/464

Conjugate

Application Notes

IHC-P: 1:100-500
IHC-F: 1:100-500
IF: 1:100-500

General Notes

This product (Catalog No. DPABH-05268) is a rabbit-derived IgG polyclonal antibody raised against human SF3A2, targeting the amino acid region 65–160 of the protein. This antibody exhibits cross-reactivity with SF3A2 from mouse, rat, chicken, dog, and cow. It has been affinity purified by Protein A. This gene encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.
DPABH-05268 is suitable for use in IHC-P (1:100–1:500), IHC-F (1:100–1:500), IF (immunofluorescence) (1:100–1:500) applications.
DPABH-05268 is supplied as a liquid formulation in 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

PRPF11; SF3a66; SAP 62; SAP-62; Spliceosome-associated protein 62; splicing factor 3a subunit 2; SF3A2_HUMAN

Entrez Gene ID

UniProt ID