Specifications
Immunogen
Recombinant full length mature protein, corresponding to amino acids 17-410 of Human Neuroserpin with 26kDa proprietary tag (AAH18043).
Applications
Application Notes
WB: 1/500 - 1/1000; IHC-P: 5 μg/ml;
Target
Alternative Names
SERPINI1; serpin peptidase inhibitor, clade I (neuroserpin), member 1; PI12, serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1; neuroserpin; PI-12; serpin I1; peptidase inhibitor 12; serine (or cysteine) proteinase inhibitor, cla
Product Background
Antigen Description
Serine protease inhibitor that inhibits plasminogen activators and plasmin but not thrombin. May be involved in the formation or reorganization of synaptic connections as well as for synaptic plasticity in the adult nervous system. May protect neurons from cell damage by tissue-type plasminogen activator.
Pathway
Validated targets of C-MYC transcriptional activation, organism-specific biosystem.
Citations
Publication ()
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COA
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