Anti-SELM monoclonal antibody, clone FQS9380

Antibody Isotype

IgG

Clone

FQS9380

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to residues on the C terminus of Human Selenoprotein M (UniProt Q8WWX9).

Conjugate

Application Notes

WB: 1/1000 - 1/10000; IHC-P: 1/50 - 1/100;

Alternative Names

SELM; selenoprotein M; selenoprotein SelM; SEPM; MGC40146;

Entrez Gene ID

UniProt ID

Antigen Description

Selenoprotein M is widely expressed and expressed highly in the mammalian brain. It is localized to the perinuclear structures (Golgi/ER). A growing body of evidence relates selenium to cancer prevention, immune system function, male fertility, cardiovascular disorder, control of the aging and neurodiseases process. Selenoproteins are thought to be responsible for the majority of these biomedical effects of selenium. Approximately 17 selenoproteins have been identified until now. Although the function of many selenoproteins are unknown, some play important roles in antioxidant mechanisms. It has been also implicated in the regulation of signaling pathways through catalysis of thiol/disulfide exchange. The roles of Selenoprotein M have not been clearly identified until present time.

Pathway

Selenium Metabolism and Selenoproteins, organism-specific biosystem; Selenium Pathway, organism-specific biosystem;