Antibody was raised against an 18 amino acid peptide near the carboxy terminus of human SEC62.
Conjugate
Unconjugated
Target
Alternative Names
SEC62; SEC62 homolog (S. cerevisiae); HTP1; TP-1; Dtrp1; TLOC1; translocation protein SEC62; hTP-1; translocation protein 1; membrane protein SEC62, S.cerevisiae, homolog of
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Pathway
Protein export; Protein processing in endoplasmic reticulum
Citations
Publication ()
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