General Notes
This product (Catalog No. DPABH-18454) is a rabbit-derived polyclonal antibody raised against human SCP2, targeting the amino acid region 1–322 of the protein. This antibody exhibits cross-reactivity with Human SCP2 from mouse and rat. It has been affinity purified by Protein A. SCP2 (Sterol carrier protein-2), also called nonspecific lipid-transfer protein, is thought to play a major role in intracellular lipid transport and metabolism. Mutations of SCP2 have been associated with diseases involving abnormalities in lipid trafficking, such as Zellweger syndrome. The alternative splicing generates 58 kDa SCPx and 13-15 kDa SCP2 proteins, both of which contain a C-terninal SCP2 domain. In addition to the SCP2 domain, SCPx also contains an amino-terminal thiolase domain. The proteolytic cleavage of SCPx occurred when it was imported into peroxisomes, giving rise to a 44-46 kDa thiolase and a 13-15 kDa SCP2.
DPABH-18454 is suitable for use in Western blot (WB) (1:300–1:1,500), IHC (1:50–1:500), IF/ICC (1:10–1:100) applications.
DPABH-18454 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
COA
Publication 
Loading ......
