Synthetic peptide: SEDAIEEEGEDGVGSPRS, corresponding to internal sequence amino acids 459-476 of Rat Nav1.6
Conjugate
Unconjugated
Target
Alternative Names
SCN8A; sodium channel, voltage gated, type VIII, alpha subunit; sodium channel protein type 8 subunit alpha; PN4; naCh6; Na+ channel; sodium channel 6; peripheral nerve protein type 4; sodium channel protein type VIII subunit alpha; voltage-gated sodium c
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. In macrophages and melanoma cells, isoform 5 may participate in the control of podosome and invadopodia formation.
Citations
Publication ()
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