Synthetic peptide corresponding to Mouse Nav1.8 aa 1850-1950 conjugated to Keyhole Limpet Haemocyanin (KLH).Database link: Q6QIY3
Conjugate
Unconjugated
Applications
Application Notes
WB: 1 μg/ml;
Target
Alternative Names
SCN10A; sodium channel, voltage-gated, type X, alpha; PN3; SNS; Nav1.8; sodium channel protein type 10 subunit alpha; voltage gated sodium channel; sensory neuron sodium channel; peripheral nerve sodium channel 3; sodium channel protein type X subunit alp
Nav1.8 protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, Nav1.8 forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Nav1.8 plays a role in neuropathic pain mechanisms.
Citations
Publication ()
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COA
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